THE ALLIANCE FOR THE PRUDENT USE OF ANTIBIOTICS INC
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Mission Statement
MISSION STATEMENT The mission of the Alliance for the Prudent Use of Antibiotics (APUA) is to strengthen global defenses against infectious disease by ensuring access to effective treatment and promoting appropriate antibiotic use to contain drug resistance. With a network of affiliated chapters in 16 countries, APUA stands as the world’s leading organization conducting research and education on antimicrobial treatment and resistance at the grassroots and global levels. Our OBJECTIVES • Increase public awareness and knowledge • Strengthen infectious disease prevention capability and treatment • Improve institutional and governmental antimicrobial policy • Build local microbiology surveillance and diagnostics capacity
About This Cause
Antibiotic resistance is one of the major public health threats of the 21st century. Since 1981, the Alliance for the Prudent Use of Antibiotics has been the premier organization dedicated to promoting appropriate antibiotic use and curbing antibiotic resistance. APUA conducts large-scale national and international research and educational projects to control and monitor antibiotic resistance. We facilitate the exchange of up-to-date information by forging national and international partnerships among scientists, healthcare providers, consumers, and policy makers. APUA’s resources include: a professional staff with expertise in medicine, microbiology, economics, health education, ecology, international program development, and health systems research; affiliations with Tufts University School of Medicine and Tufts Health Plan; APUA chapters in more than 60 countries; and an advisory board of leading clinical and scientific experts including Nobel laureates and members of national academies of medicine and science. APUA’s multidisciplinary research program applies basic science, epidemiology, and surveillance to identify trends in susceptible and drug resistant infections and promising interventions. By conducting research on many aspects of this far-reaching public health problem, APUA’s work advances the ecological approach towards “One World, One Health.” APUA studies have provided groundbreaking data which have influenced national and international public health policy on antimicrobial resistance, including: the first hospital study to rigorously document the economic burden of drug resistance; studies used by the FDA to support their pursuit of curbing the non-therapeutic use of antibiotics in food animals; and reports to promote targeted sanitation and hygiene measures to control the spread of infectious disease. APUA staff and board members regularly publish the results of their research and consult in national and international planning initiatives with IDSA, USFDA Anti-Infective Advisory Committee, WHO Patient Safety Committee, Global Development Council, Institute of Medicine, Center for Global Development, and others. APUA is the sister organization of the Center for Adaptation Genetics and Drug Resistance at the Tufts University School of Medicine, allowing us to enjoy a close relationship with Tufts Medical Center and its affiliates: Cambridge Hospital, Metro West Medical Center, St. Elizabeth’s Medical Center, Lahey Clinic Medical Center, and Tufts Managed Care Institute. We have also conducted projects with the Tufts University Friedman School of Nutrition and the Tufts University Cummings School of Veterinary Medicine. Antibiotic resistance is fueled by misuse and overuse of antibiotics. Bacteria become resistant to the very medicines developed to treat and cure the infection they cause. Major ARIs (antibiotic resistant infections) include methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant enterococcus (VRE), C. difficile and a growing number of deadly Gram-negative infections. APUA specializes in study of drug-resistant infections – one of the most expensive types of healthcare-acquired infection and the most difficult to contain. APUA’s research interests are focused on documenting and controlling bacterial infections through improved surveillance, antibiotic stewardship and infection control. APUA has a long history of working in collaboration with local, national, and international organizations. We have developed protocols for projects with PAHO, USAID, U.S. CDC, USDA-ARS, NIH, and NIAID; state organizations such as the Massachusetts Department of Public Health and the Massachusetts Infectious Disease Society; corporations such as Pfizer, Clorox, Procter & Gamble, and bioMérieux; and other nonprofit organizations such as the Gates Foundation and the Pew Charitable Trusts. We have also worked closely with both domestic and international government healthcare infrastructure.