TYPE 1 DIABETES INTERNATIONAL FOUNDATION

ORLAND PARK, Illinois, 60467-8469 United States

Mission Statement

The Diabetes International Foundation is committed to spreading awareness of diabetes; the symptoms, different types of diabetes and treatments available through networking and partnering with corporate companies, health clinics, pharmacies and schools across the United States. We are dedicated to raising funds for education and diabetes research to ultimately identify a cure.

About This Cause

There are many different types of diabetes. Researchers continue to identify other forms that exist called Monogenic Diabetes or MODY (Maturity Onset Diabetes of the Young). Monogenic Diabetes is caused from a single gene mutation and the symptoms mimic Type 1 and Type 2 Diabetes. The difference? Once a patient is identified and properly diagnosed through genetic testing as having Monogenic Diabetes, at times, the patient is able to transition off of insulin shots or insulin pump therapy and take oral diabetes meds daily to manage their diabetes successfully without carb counting and finger pricking multiple times per day. Doctors and scientists believe there may be up to 500,000 people in the United States and 7,000,000 in the world that are misdiagnosed as having Type 1 or Type 2 Diabetes, and may have Monogenic Diabetes. Once identified, truly life-changing for not only the patient, but the whole family. Red flags would be: Diagnosed with Type 1 Diabetes as a baby (Neonatal Diabetes). According to the experts, Diabetes diagnosed less than 6 months of age usually has an identifiable monogenic cause (around 75-80%). Those diagnosed between 6-12 months old have a much smaller chance of having a monogenic cause (around 5%). The experts suggest all those diagnosed under a year of age be genetically tested. Other markers to look for after 1 year of age: -Diagnosed with Type 1 Diabetes but have negative diabetes related antibodies -Diagnosed with Type 1 Diabetes but using small amounts of insulin to manage diabetes -Family history of diabetes in multiple generations Chronic mild fasting high sugars may be related to one form of monogenic diabetes (MODY 2 or GCK-MODY) which has a distinctive glucose pattern. Family members affected have chronically raised morning blood sugars throughout their lives. Some may be described as having type 2 diabetes, pre-diabetes or impaired fasting glucose. Multiple members and generations of a family with this pattern alert the experts to the possibility of this form of diabetes. The features are: -Fasting sugars of 100-140mg/dl (5.6 - 7.5mmol/l) for many years -2 or 3 generations of diabetes diagnosed at a young age -A HbA1c that does not go over 7.8% -Blood sugars rarely ever go above 250mg/dl (14mmol/l) -Negative diabetes related antibody testing -Persistently detectable C-Peptide -No history of diabetic ketoacidosis Diabetes in adolescence/early childhood may be related to a group of gene causes (MODY 1 and MODY 3) that typically manifest before 30 years of age and are often misdiagnosed as type 1 diabetes mellitus or called unusual forms of type 2 diabetes. These can be hard to distinguish from the more common types. The following features suggest these forms: -Negative diabetes-related antibody testing -Persistently detectable C-Peptide -2 or 3 generations of diabetes diagnosed at a young age -High sensitivity to sulfonylurea medications -No history of diabetic ketoacidosis Diabetes and renal (kidney) cysts is a form of monogenic diabetes (MODY 5) that often results in diabetes in combination with a structural kidney or kidney tract problem. Features that distinguish MODY 5 from other forms of diabetes include: -A 2 or 3 generation family history of renal cysts -A family history of structural problems of the uterus or kidneys -Diabetes in multiple family members with renal cysts -No history of diabetic ketoacidosis For further detailed information, please visit our website: www.type1diabetesintl.org or www.diabetesintl.org

TYPE 1 DIABETES INTERNATIONAL FOUNDATION
10539 Wood Duck Ln
ORLAND PARK, Illinois 60467-8469
United States
Phone 708-790-5518
Unique Identifier 451969245